Average pregnancy rates decline gradually with age and do so more sharply after age 37. This is striking when one considers that menopause, the time when the ovary is effectively devoid of eggs, occurs on average at age 51. Therefore, for many women fertility begins to decline 15-20 years or more before the ovary is depleted of eggs. The actual degree and rate of decline varies from woman to woman. The aging of the eggs occurs because women make no new eggs after birth, in contrast to men who continue to make new sperm throughout adult life.
As fertility declines, the incidence of miscarriage also rises. Estimates for miscarriage rates are 10-20% under 35 years, 15-30% for 35-39 years, and about 35-60% for over 40 years.
This information implies that the functional capacity of the egg to create a live-born baby declines long before depletion of all eggs from the ovary.
- Determining ovarian reserve
- General information
- Anti-mullerian Hormone
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